Research Article
Development and External Validation of Machine Learning-Based Models for Predicting Lung Metastasis in Kidney Cancer: A Large Population-Based Study
Table 3
Univariate and multivariate logistic regression analysis.
| Variables | Univariate analysis | Multivariate analysis | OR | | OR | |
| Age | 1.012 | <0.001 | 1.007 | 0.003 |
| Laterality | Left | Reference | Reference | Reference | Reference | Right | 0.968 | 0.515 | ā | ā |
| Sex | Female | Reference | Reference | Reference | Reference | Male | 1.49 | <0.001 | 1.184 | 0.004 |
| Race | Asian | Reference | Reference | Reference | Reference | Black | 0.539 | <0.001 | 0.613 | <0.001 | Other | 0.604 | 0.019 | 0.604 | 0.037 | White | 0.818 | 0.033 | 0.821 | 0.063 |
| T_stage | T1 | Reference | Reference | Reference | Reference | T2 | 10.922 | <0.001 | 4.591 | <0.001 | T3 | 19.599 | <0.001 | 5.885 | <0.001 | T4 | 79.462 | <0.001 | 11.172 | <0.001 |
| N_stage | N0 | Reference | Reference | Reference | Reference | N1 | 17.245 | <0.001 | 4.415 | <0.001 | Tumor_size | 1.024 | <0.001 | 1.009 | <0.001 |
| Histology | 8120 | Reference | Reference | Reference | Reference | 8255 | 0.401 | <0.001 | 1.083 | 0.782 | 8260 | 0.071 | <0.001 | 0.462 | 0.007 | 8310 | 0.206 | <0.001 | 1.217 | 0.451 | 8312 | 0.301 | <0.001 | 1.419 | 0.192 | 8317 | 0.038 | <0.001 | 0.196 | <0.001 | Other | 0.96 | 0.868 | 1.497 | 0.142 |
| Grade | I | Reference | Reference | Reference | Reference | II | 1.755 | <0.001 | 1.235 | 0.214 | III | 7.213 | <0.001 | 2.264 | <0.001 | IV | 26.042 | <0.001 | 3.438 | <0.001 |
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The bold values indicate that the p value is less than 0.05.
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