Research Article

Development and External Validation of Machine Learning-Based Models for Predicting Lung Metastasis in Kidney Cancer: A Large Population-Based Study

Table 4

Predictive performance of algorithms in internal and external test cohorts.

ModelsInternal testExternal test
AUCAccuracySensitivitySpecificityPrecisionRecallF1 scoreAUCAccuracySensitivitySpecificityPrecisionRecallF1 score

LR0.9030.7870.8730.7830.1800.8730.2990.8960.8660.750.8720.2310.750.353
RF0.7910.8850.6610.8970.2600.6610.3730.7030.8760.50.8950.1970.50.283
SVM0.610.9380.3260.9720.3890.3260.3550.6740.9190.1670.9570.1670.1670.167
XGB0.9130.8120.8730.8090.2000.8730.3250.9040.8720.750.8780.2400.750.364
DT0.8200.8310.7630.8350.2020.7630.3190.6900.8960.4580.9190.2240.4580.301
ANN0.9060.7920.8750.7870.1840.8750.3040.8910.8430.7920.8460.2090.7920.331

LR: logistic regression, RF: random forest, SVM: supporting vector machine, XGB: extreme gradient boosting, DT: decision tree, and ANN: artificial neural network.