α-Klotho: An Early Risk-Predictive Biomarker for Acute Kidney Injury in Patients with Acute Myocardial Infarction
Table 3
The areas under the receiver operating characteristic curves for serum levels of α-Klotho and other conventional risk factors to predict AKI after AMI.
AUROC
95% CI
value
Cut-off value
Sensitivity
Specificity
SCr at admission (μmol/L)
0.583
0.460–0.706
0.179
70.5
0.741
0.444
eGFR at admission (ml/min1.73 m2)
0.698
0.579–0.817
0.001
75.75
0.462
0.883
SBP (mmHg)
0.726
0.601–0.851
<0.001
100
0.556
0.914
Hgb (g/L)
0.680
0.559–0.801
0.003
136
0.741
0.614
LVEF (%)
0.765
0.657–0.873
<0.001
54.4
0.630
0.866
BNP at admission (ng/ml)
0.717
0.593–0.842
0.001
297.8
0.522
0.843
Klotho at admission (pg/ml)
0.792
0.706–0.878
<0.001
516.9
0.778
0.694
AUROC, area under the receiver operating characteristic curves; CI, confidence interval.
