Changes in Serum Concentrations of Bone Turnover Markers in Healthy Pregnant Women

Figure 2

The trend of bone turnover markers in different stages of pregnancy: PINP (a), N-MID (b), β-CTX (c), β-CTX/PINP ratio (d), and β-CTX/N-MID ratio (e) at each trimester during pregnancy. Statistics were calculated by the Kruskal–Wallis test. ns,  ≥ 0.05;  < 0.05;  < 0.01;  < 0.001. PINP, procollagen type I N-propeptide; N-MID, N-terminal osteocalcin; β-CTX, C-terminal telopeptide of type I collagen.

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