Prognostic Value of Neutrophil-to-Lymphocyte Ratio and Vaccination for Negative Conversion Time of Nucleic Acid in Nonsevere COVID-19 Patients Infected by SARS-CoV-2 Omicron Variant

Table 2

Univariable and multivariate Cox regression analyses for risk factors associated with the NCT of nucleic acid in nonsevere COVID-19 patients infected by the SARS-CoV-2 Omicron variant.

Variables	Univariate analysis		Multivariate analysis
	HR (95% CI)	value	HR (95% CI)	value
Aged (≥65 years)	0.743 (0.568–0.971)	0.030	0.812 (0.610–1.079)	0.151
Male	0.787 (0.604–1.025)	0.075	0.826 (0.621–1.098)	0.187
Comorbidities ≥ 1	0.973 (0.742–1.277)	0.845	1.090 (0.823–1.443)	0.548
Vaccinated ≥ 1 dose	1.699 (1.283–2.250)	<0.001	1.536 (1.147–2.058)	0.004
Moderate illness	0.662 (0.480–0.912)	0.012	0.831 (0.590–1.171)	0.290
Low eosinophil level (<0.02 × 10^9 cells/L)	0.847 (0.596–1.202)	0.351	0.910 (0.634–1.307)	0.611
Monocytosis (>0.6 × 10^9 cells/L)	0.842 (0.611–1.159)	0.291	1.016 (0.719–1.435)	0.929
NLR > 2.22	0.604 (0.461–0.790)	<0.001	0.718 (0.534–0.964)	0.028

HR: hazard ratio; CI: confidence interval; NLR: neutrophil-to-lymphocyte ratio; NCT: negative conversion time. Bold value: p < 0.05.