Research Article

Retinal Microvascular Density and Perfusion during an Insulin-Induced Hypoglycemia Episode: A Warning Call

Table 2

Vascular reactivity to hypoglycemia event.

3 × 3 mm protocolVascular perfusion (%)Vascular density (%)
StagesHealthy (n = 42)DM without DR (n = 37)DM with DR (n = 18)valueHealthy (n = 42)DM without DR (n = 37)DM with DR (n = 18)value

Baseline34.58 (3.5)33.54 (2.79)31.08 (4.38)0.00919.62 (1.46)18.54 (2.02)16.85 (3.28)0.002
Hypoglycemia32.42 (3.74)31.71 (3.77)29.46 (4.46)0.09518.46 (2.32)17.73 (2.58)16.08 (3.04)0.034
Return to normoglycemia33.83 (2.74)33.08 (4.1)30.15 (4.24)0.01619.17 (1.6)18.42 (2.5)16.38 (2.98)0.004
value0.0110.0110.0010.0410.0160.094

SD: standard deviation; IQR: interquartile range; DM: diabetes mellitus. Bold values represent the statistically significant values (P < 0.05).