Mediterranean-Oriented Dietary Intervention Is Effective to Reduce Liver Steatosis in Patients with Nonalcoholic Fatty Liver Disease: Results from an Italian Clinical Trial
Table 3
Anthropometric values, laboratory findings, and Medscore among NAFLD patients and healthy controls at baseline (T0) and at the end of the study (T12): means (SD) and ΔT0–T12 as means (SD) in the differences of the values at T0 and at T12.
NAFLD patients (58)
Healthy controls (73)
T0
T12
ΔT0–T12
T0
T12
ΔT0–T12
BMI (kg/m2)
31.4 (5.5)
30.5 (5.6)
0.9 (1.2)§
<0.001
24.0 (3.8)
24.0 (3.8)
0.0 (0.9)§
0.97
Waist circumference (cm)
105 (14)
104 (13)
0.9 (4.7)#
0.16
87 (11)
88 (11)
−0.8 (3.8)#
0.04
Total cholesterol (mg/dL)
207 (34)
211 (35)
−3.6 (28)
0.29
196 (40)
200 (35)
−4.4 (24)
0.13
HDL
50 (12)
53 (14)
−3.2 (7.5)
<0.01
66 (18)
66 (17)
−0.4 (8.1)
0.43
LDL
128 (31)
132 (29)
−3.7 (23)
0.22
114 (38)
117 (34)
−3.1 (22)
0.17
Triglycerides (mg/dL)
152 (96)
128 (58)
24 (76)
0.06
82 (39)
86 (43)
−4.1 (31)
0.60
Glycemia (mg/dL)
98 (19)
99 (20)
−0.5 (14)
0.57
85 (9)
85 (10)
0.2
0.47
Insulinemia (μU/mL)
16 (15)
13 (9)
2.4 (11)
0.12
5 (4)
5 (4)
−0.1
0.94
AST (U/L)
22 (10)
22 (8)
0.2
0.71
19 (7)
21 (8)
−1.4 (7)
0.05
ALT (U/L)
41 (21)
40 (21)
1.6 (21)
0.43
29 (19)
30 (19)
−0.7 (15)
0.35
HOMA-IR index
3.9 (4.5)
3.6 (3.2)
0.3 (4.2)
0.23
1.1 (0.9)
1.1 (0.9)
0.0
0.86
Medscore
12 (3)
16 (3)
−3.2 (3.1)§
<0.001
15 (4)
15 (4)
−0.2§
0.20
§ and # for the comparison between the differences among NAFLD patients and healthy controls (according to Wilcoxon nonparametric test for paired data). Mann–Whitney test.
