Network Pharmacology Analysis of the Therapeutic Potential of Colchicine in Acute Lung Injury

Figure 2

The flowchart to identify the colchicine-ALI interaction genes. The number attached to the database name refers to the number of genes acquired from the database. After duplicated removal, 253 ALI-related genes were acquired from the DisGeNET, Therapeutic Target Database, Comparative Toxicogenomics Database, and GSE10474. 389 verified or predictive colchicine targets were identified based on the DrugBank, BATMAN-TCM, STITCH, and SwissTargetPrediction. Finally, a total of 23 potential colchicine-ALI interaction genes were acquired. ALI: acute lung injury.