Simvastatin Does Not Affect Vitamin D Status, but Low Vitamin D Levels Are Associated with Dyslipidemia: Results from a Randomised, Controlled Trial

Table 1

Baseline characteristics by study group (mean ± sem).

	Placebo (𝑛=38)	Simvastatin (𝑛=39)	𝑃-value (𝑛=77)
Age (years)(1)	64 (53–72)	63 (53–72)	.70
Years postmenopausal(1)	18 (6–44)	19 (7–31)	.80
Scale body weight (kg)	69.6±1.4	64.6±1.8	.04
Body mass index (kg/m2)	26.4±0.5	24.7±0.7	.04
Biochemestry
Plasma
Calcium (adj.) (mmol/L)	2.44±0.01	2.46±0.01	.17
Creatinine (mol/L)	77±2	78±2	.82
Total cholesterol (mmol/L)	6.4±0.1	6.5±0.2	.69
HDL cholesterol (mmol/L)	1.8±0.1	2.0±0.1	.14
LDL cholesterol (mmol/L)	4.0±0.1	4.0±0.2	.99
Triglycerides (mmol/L)	1.3±0.1	1.1±0.1	.08
P-PTH (pmol/L)	4.2±0.2	4.4±0.2	.39
25OHD (nmol/L)	70±4	71±4	.89
25OHD <25 nmol/L, 𝑁 (%)	2 (5%)	1 (3%)	.54
25OHD <50 nmol/L, 𝑁 (%)	7 (18%)	4 (10%)	.35
25OHD <80 nmol/L, 𝑁 (%)	25 (66%)	26 (67%)	.94

(1)Median (range).