The Serum Level of Fibroblast Growth Factor-23 and Calcium-Phosphate Homeostasis in Obese Perimenopausal Women
Table 1
Characteristics of obese women and controls.
Obese
Controls
Age (yrs)
55.4 (53.6–57.1)
50.4 (46.0–54.7)
Body mass (kg)
94.5 (90.6–98.3)
62.4 (59.2–65.6)
BMI (kg/m2)
36.5 (35.1–37.9)
23.5 (22.4–24.6)
Waist circumference (cm)
106.7 (103.3–110.1)
82.3 (78.3–86.4)
Fat tissue content (%)
49.6 (47.8–51.3)
35.2 (32.3–38.2)
BMD L2–L4 (g/cm2)
1.196 (1.133–1.259)
1.035 (0.930–1.140)
BMD proximal femur (g/cm2)
1.026 (0.976–1.076)
0.858 (0.808–0.909)
BMC L2–L4 (g/cm)
65.0 (60.7–69.3)
56.4 (51.1–61.7)
BMC proximal femur (g/cm)
4.87 (4.58–5.16)
4.23 (3.81–4.64)
Creatinine (mg/dL)
0.64 (0.61–0.67)
0.66 (0.61–0.71)
eGFR (mL/min)
97.4 (94.4–100.3)
99.5 (92.7–106.3)
Total calcium (mmol/L)
2.22 (2.18–2.25)
2.19 (2.13–2.25)
Phosphorus (mmol/L)
1.04 (1.00–1.08)
1.15 (1.09–1.21)
25(OH)D3 (ng/mL)
30.2 (26.2–34.2)
43.5 (34.8–52.1)
Osteocalcin (ng/mL)
19.1 (17.4–20.9)
24.0 (20.4–27.6)
iPTH (pg/mL)
47.3 (42.2–52.3)
35.4 (30.4–40.4)
CTX1 (ng/mL)
0.24 (0.21–0.27)
0.28 (0.21–0.35)
iFGF-23 (ng/mL)
9.14 (7.12–11.15)
6.44 (5.70–7.18)
PTH: parathormone; CTX1: C-terminal telopeptide of collagen type I; BMI: body mass, BMD: bone mineral density, BMC: bone mineral content, iFGF-23: intact fibroblast growth factor 23, eGFR: estimated glomerular filtration rate.
