Change of Body Composition and Adipokines and Their Relationship with Insulin Resistance across Pubertal Development in Obese and Nonobese Chinese Children: The BCAMS Study

Table 2

Stepwise forward multiple regression analyses for Ln HOMA-IR with subjects stratified by sex and weight.

	Parameters	𝛽±SE	Beta	𝑃
Boys (𝑛=1616)
Normal weight; (𝑅^2=0.247)	Leptin*	0.227±0.027	0.304	<0.001
	Tanner stage	0.178±0.021	0.303	<0.001
	TG*	0.262±0.066	0.149	<0.001
Overweight; (𝑅^2=0.274)	Leptin*	0.208±0.039	0.286	<0.001
	Adiponectin*	−0.139±0.061	−0.122	0.023
	Tanner stage	0.120±0.033	0.224	<0.001
	TG*	0.266±0.078	0.181	0.001
	SBP	0.007±0.003	0.153	0.011
Obesity; (𝑅^2=0.288)	Leptin*	0.208±0.030	0.260	<0.001
	Adiponectin*	−0.138±0.040	−0.119	0.001
	Waist circumference	0.008±0.003	0.127	0.006
	Tanner stage	0.067±0.023	0.124	0.004
	TG*	0.215±0.050	0.145	<0.001
	SBP	0.007±0.002	0.143	<0.001
Girls (𝑛=1607)
Normal weight; (𝑅^2=0.324)	Leptin*	0.227±0.023	0.348	<0.001
	Tanner stage	0.075±0.018	0.148	<0.001
	TG*	0.203±0.048	0.125	<0.001
	SBP	0.009±0.002	0.154	<0.001
Overweight; (𝑅^2=0.260)	Leptin*	0.238±0.040	0.313	<0.001
	Adiponectin*	−0.145±0.056	−0.133	0.010
	Tanner stage	0.070±0.025	0.158	0.005
	TG*	0.224±0.077	0.152	0.004
	SBP	0.010±0.003	0.169	0.001
Obesity; (𝑅^2=0.362)	Leptin*	0.160±0.037	0.198	<0.001
	Waist circumference	0.027±0.003	0.408	<0.001
	TG*	0.267±0.062	0.178	<0.001

Independent parameters: leptin, diponectin, Tanner stage, TG, SBP, DBP, HDL-C, waist circumference, or BMI z-score or FAT%; *Skewed distributions were logarithmically transformed for analysis. Abbreviations as Table 1.