Review Article

Suppression of Aldosterone Synthesis and Secretion by Channel Antagonists

Figure 1

Overview of steroid biosynthesis in adrenal cells. Asterisks (*) and the symbol (#) indicate enzymes and the adrenal steroid that may be modulated by dihydropyridine CCBs. Solid line: steroid biosynthesis in cells of the zona glomerulosa; dotted line: steroid biosynthesis in cells of the zona fasciculate; broken line: steroid biosynthesis in cells of the zona reticularis.
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