Factors Associated with the Decline of Kidney Function Differ among eGFR Strata in Subjects with Type 2 Diabetes Mellitus

Table 2

Multiple linear regression analysis of annual eGFR decline in all subjects. Multiple linear regression analysis of annual GFR reduction was performed. AER was transformed to the common logarithm for calculations. SBP: systolic blood pressure, AER: albumin excretion rate. Adjusted 𝑅²=0.213, 𝑃<0.001.

Parameter	Partial regression coefficient (𝛽)	Standard error; (S.E.)	𝑃 value
Age (years)	0.096	0.017	<0.01
Male: 1, female: 0	0.100	0.343	<0.01
SBP (mmHg)	0.073	0.008	<0.01
HbA1c (%)	0.240	0.079	<0.001
Log10 AER (μg/min)	0.228	0.212	<0.001
eGFR strata (1–3)	−0.288	−0.244	<0.001
Retinopathy: 1, none: 0	0.052	0.323	0.051
Hemoglobin (g/L)	−0.102	−0.115	<0.01