Factors Associated with the Decline of Kidney Function Differ among eGFR Strata in Subjects with Type 2 Diabetes Mellitus

Table 3

Multiple linear regression analysis of annual eGFR decline stratified by eGFR strata. Multiple linear regression analysis of annual eGFR reduction was performed. Adjusted 𝑅² and 𝑃 values of multiple regression model of stratum 1–3 were 𝑅²=0.130 and 𝑃<0.001, 𝑅²=0.154 and 𝑃<0.001, and 𝑅²=0.469 and 𝑃<0.001, respectively. AER was transformed to the common logarithm for calculations. SBP: systolic blood pressure, AER: albumin excretion rate.

Parameter		Stratum 1				Stratum 2				Stratum 3
	𝛽	SE	𝑃 value		𝛽	SE	𝑃 value		𝛽	SE	𝑃 value
Age (years)	0.069	0.039	n.s.		0.153	0.153	<0.001		−0.071	0.040	n.s.
Male: 1, female: 0	0.083	0.754	n.s.		0.119	0.381	<0.01		0.181	0.726	<0.05
SBP (mmHg)	0.045	0.017	n.s.		0.100	0.010	<0.01		0.128	0.017	n.s.
HbA1c (%)	0.272	0.165	<0.001		0.236	0.091	<0.001		0.128	0.170	n.s.
Log10 AER (μg/min)	0.185	0.485	<0.001		0.195	0.246	<0.001		0.516	0.388	<0.001
Retinopathy: 1, None: 0	0.085	0.730	n.s.		0.054	0.357	n.s.		−0.075	0.647	n.s.
Hemoglobin (g/L)	−0.086	0.269	n.s.		−0.071	0.132	n.s.		−0.249	0.201	<0.01