Arginine 16 Glycine Polymorphism in β2-Adrenergic Receptor Gene Is Associated with Obesity, Hyperlipidemia, Hyperleptinemia, and Insulin Resistance in Saudis
Table 5
Correlation between fasting glucose and the anthropometric parameters and lipids in individuals with different Arg16Gly genotypes.
Correlation between glucose and different parameters in different genotypes
BMI kg/m2
Waist cm
Hip cm
W/H ratio
Chol mmol/L
TAG mmol/L
HDL mmol/L
LDL mmol/L
Leptin ng/mL
Insulin pmol/L
Homa IR
Arg/Arg
r
0.28**
0.39**
0.26**
0.42**
0.24**
0.31**
−0.27**
0.30**
0.19**
0.26**
0.47**
(189)
P
0.000
0.000
0.000
0.000
0.001
0.0001
0.0001
0.0001
0.008
0.0001
0.000
Arg/Gly
r
0.15
0.21
0.14
0.25*
0.42**
−0.03
0.13
0.47**
0.10
0.17
0.38**
(68)
P
0.24
0.08
0.25
0.04
0.000
0.79
0.29
0.000
0.41
0.17
0.001
Gly/Gly
r
0.18
0.16
0.14
0.12
0.003
0.11
−0.23
0.01
0.03
0.31**
0.44**
( 70)
P
0.14
0.18
0.26
0.31
0.98
0.36
0.06
0.92
0.83
0.009
0.000
Abbreviations: BMI: body mass index; W/H: waist hip ratio; r: pearson correlation coefficient; Chol: cholesterol; TAG: triglyceride; HDL: HDL-cholesterol; LDL: LDL-cholesterol; **significant at the 0.0001 level.
