Thermogenic Effect of Glucose in Hypothyroid Subjects

Table 1

Comparison of healthy and hypothyroid females: subjects’ characteristics and results of OGTT test.

	Healthy subjects	Hypothyroid patients	𝑃 value
𝑛	34	32
Age (yr)	38.14±1.85	38.53±2.38	NS
BMI (kg/m^2)	27.77±0.86	28.99±0.91	NS
TSH (mIU/L)	1.51±0.22	5.03±0.66	<0.001
fT3 (ng/L)	3.27±0.11	1.25±0.11	<0.0001
fT4 (ng/L)	12.43±0.49	7.34±0.57	<0.0001
Triglycerides (mg/dL)	52.16±9.19	56.63±5.27	NS
Cholesterol (total) (mg/dL)	150.33±9.86	125.90±8.14	NS
HDL-cholesterol (mg/dL)	51.84±4.08	43.35±3.89	NS
LDL-cholesterol (mg/dL)	92.51±6.93	71.32±8.23	NS
RMR (kJ/h/kg body wt)	3.17±0.17	2.50±0.07	<0.0001
TEG (kJ)	55.40±7.32	19.68±3.90	<0.0004
BGauc (mmol/L·min)	188.41±15.84	286.79±23.65	<0.003
IRIauc (mU/L·min)	4987.72±583.88	7563.27±863.65	<0.03
𝐴max (nmol/L)	0.30±0.07	0.69±0.08	<0.0001
NAmax (nmol/L)	2.54±0.30	6.42±0.86	<0.0002