Liraglutide Exerts Antidiabetic Effect via PTP1B and PI3K/Akt2 Signaling Pathway in Skeletal Muscle of KKAy Mice
Figure 6
Effects of liraglutide on p-Akt2 and Akt2 expressions in skeletal muscle. (a) Expression in skeletal muscle of p-Akt2 and Akt2 mRNA in normal, model, or liraglutide group. Gene expression was measured by RT-PCR. Relative p-Akt2 and Akt2 mRNA abundance was normalized by β-actin. Data were shown as mean ± SD, , versus model group, . (b) Expression of p-Akt2 and Akt2 protein in skeletal muscle from normal, model, or liraglutide group. Lysates from freshly isolated skeletal muscle tissues were measured for p-Akt2 and Akt2 expression by Western blot analysis. Results were shown as mean ± SEM, , versus model group, .
