Clinical Characteristics Related to Central Lymph Node Metastasis in cN0 Papillary Thyroid Carcinoma: A Retrospective Study of 916 Patients

Table 2

Correlation between clinical factors and CLN metastasis: univariate analysis.

Term	Cervical lymph node metastasis
	Negative	Positive	Case number	Positive rate	P value
Gender					0.000
Male	63	123	186	66.13%
Female	361	369	730	50.55%
Age (years)					0.000
≤25	5	45	50	90.00%	(0.000)*
25~35	46	113	159	71.07%
35~45	161	165	326	50.61%
45~55	133	114	247	46.15%
55~65	61	39	100	39.00%
65	18	16	34	47.06%
Tumor size (cm)					0.000
≤0.5	181	54	235	22.98%	(0.000)**
0.5~1.0	188	164	352	46.59%
1.0~1.5	64	108	172	62.79%
1.5~2.0	21	72	93	77.42%
2.0	30	135	165	81.82%
Tumor number
Solitary	307	328	635	51.65%	0.534
Multiple	177	205	382	53.66%
Capsule invasion
Absent	363	282	645	43.72%	0.000
Present	68	108	171	63.16%
Extracapsular	53	148	201	73.63%
Tumor location					0.000
Lower pole	106	53	159	33.33%
Middle pole	127	152	279	54.48%
Upper pole	68	95	163	58.28%
Whole lobe	6	28	34	82.35%

*Age ≤ 35 years versus age 35 years.
 cm versus  cm.