Alpha Lipoic Acid Modulated High Glucose-Induced Rat Mesangial Cell Dysfunction via mTOR/p70S6K/4E-BP1 Pathway

Figure 3

Effect of LA on the secretions of FN and collagen-I in high glucose-treated mesangial cells. Supernatants were assayed by ELISA after treatment with different concentration of LA for 24 hours. Values are given as mean ± SD from 3 independent experiments in quadruplicate and is considered statistically significant. Note: ^* versus NG; ^# versus HG. Abbreviations: NG, normal glucose (5 mM); Man (5 mM glucose + 25 mM mannitol); HG, high glucose (30 mM).

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