[Retracted] Glycolipid Metabolism Disorder in the Liver of Obese Mice Is Improved by TUDCA via the Restoration of Defective Hepatic Autophagy

Figure 1

Effects of TUDCA on systemic glucose homeostasis and insulin sensitivity in obese mice. All analyses were performed in mice fed a normal diet (ND) or a high-fat diet (HFD) for 8 weeks and then injected daily with 500 mg/kg of TUDCA or with vehicle (Veh) for 8 weeks. (a) Body weight. (b) Blood glucose. (c) Serum insulin. (d) Glucose tolerance testing (GTT). (e) Insulin tolerance testing (ITT). (f) Area under the curve by GTT. (g) Area under the curve by ITT. Fifteen mice per group were analyzed. The data was expressed as mean ± SEM in each bar graph. (HFD/TUDCA versus HFD/Veh). (HFD/Veh versus ND/Veh).

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