Research Article

The Blocking on the Cathepsin B and Fibronectin Accumulation in Kidney Glomeruli of Diabetic Rats

Table 1

The characteristics of treatment groups.

GroupsGlucoseCreatinine UreaHCO3FibronectinCathepsin B
mg/dLmg/dLmg/dLmmol/Lμg/mLμIU/mL

DM
 Mean ± SD746.6 ± 47.50.66 ± 0.1162.6 ± 16.125.5 ± 1.120.91 ± 4.4744.61 ± 11.88
 Median (range)763.0 (667.0–793.0)0.7 (0.5–0.8)64.0 (43.0–81.0)25.8 (24.3–26.8)20.23 (15.06–27.54)41.03 (21.33–63.85)
EN
 Mean ± SD706.8 ± 68.80.54 ± 0.1761.6 ± 8.427.2 ± 1.825.08 ± 1.7449.6 ± 6.60
 Median (range)703.5 (607.0–812.0)0.5 (0.3–0.9)61.5 (48.0–75.0)27.1 (24.7–29.5)25.59 (22.62–26.78)46.57 (43.65–60.46)
LOS
 Mean ± SD724.7 ± 99.00.66 ± 0.1367.2 ± 15.824.7 ± 2.921.04 ± 2.5249.08 ± 10.75
 Median (range)709.0 (577.0–856.0)0.6 (0.5–0.9)64.0 (51.0–105.0)23.1 (21.7–28.3)20.08 (18.70–24.94)45.49 (39.07–66.40)
EN + LOS
 Mean ± SD764.9 ± 61.00.57 ± 0.0975.3 ± 17.725.8 ± 2.823.58 ± 3.7450.54 ± 22.79
 Median (range)776.0 (657.0–833.0)0.5 (0.5–0.7)71.0 (53.0–116.0)24.5 (21.9–29.8)25.08 (16.62–27.06)48.25 (25.63–80.59)
SPIR
 Mean ± SD679.0 ± 82.00.61 ± 0.1259.6 ± 10.926.1 ± 2.622.31 ± 3.0244.7 ± 7.91
 Median (range)670.0 (570.0–834.0)0.6 (0.4–0.8)59.0 (47.0–80.0)26.5 (22.2–30.0)23.37 (17.28–25.55)48.70 (26.88–51.10)
DIH
 Mean ± SD680.6 ± 159.70.64 ± 0.0959.8 ± 13.825.9 ± 2.323.87 ± 2.4938.98 ± 12.90
 Median (range)699.0 (380.0–858.0)0.6 (0.5–0.8)63.5 (36.0–75.0)26.2 (21.6–28.9)23.95 (20.39–27.74)37.07 (23.09–56.56)

ANOVA testNSNSNSNSNSNS

The results are presented as mean ± SD and median (range). Statistically significant differences between the groups have been shown, the levels of significance in the 95% confidence interval.