The Blocking on the Cathepsin B and Fibronectin Accumulation in Kidney Glomeruli of Diabetic Rats
Table 1
The characteristics of treatment groups.
Groups
Glucose
Creatinine
Urea
HCO3
Fibronectin
Cathepsin B
mg/dL
mg/dL
mg/dL
mmol/L
μg/mL
μIU/mL
DM
Mean ± SD
746.6 ± 47.5
0.66 ± 0.11
62.6 ± 16.1
25.5 ± 1.1
20.91 ± 4.47
44.61 ± 11.88
Median (range)
763.0 (667.0–793.0)
0.7 (0.5–0.8)
64.0 (43.0–81.0)
25.8 (24.3–26.8)
20.23 (15.06–27.54)
41.03 (21.33–63.85)
EN
Mean ± SD
706.8 ± 68.8
0.54 ± 0.17
61.6 ± 8.4
27.2 ± 1.8
25.08 ± 1.74
49.6 ± 6.60
Median (range)
703.5 (607.0–812.0)
0.5 (0.3–0.9)
61.5 (48.0–75.0)
27.1 (24.7–29.5)
25.59 (22.62–26.78)
46.57 (43.65–60.46)
LOS
Mean ± SD
724.7 ± 99.0
0.66 ± 0.13
67.2 ± 15.8
24.7 ± 2.9
21.04 ± 2.52
49.08 ± 10.75
Median (range)
709.0 (577.0–856.0)
0.6 (0.5–0.9)
64.0 (51.0–105.0)
23.1 (21.7–28.3)
20.08 (18.70–24.94)
45.49 (39.07–66.40)
EN + LOS
Mean ± SD
764.9 ± 61.0
0.57 ± 0.09
75.3 ± 17.7
25.8 ± 2.8
23.58 ± 3.74
50.54 ± 22.79
Median (range)
776.0 (657.0–833.0)
0.5 (0.5–0.7)
71.0 (53.0–116.0)
24.5 (21.9–29.8)
25.08 (16.62–27.06)
48.25 (25.63–80.59)
SPIR
Mean ± SD
679.0 ± 82.0
0.61 ± 0.12
59.6 ± 10.9
26.1 ± 2.6
22.31 ± 3.02
44.7 ± 7.91
Median (range)
670.0 (570.0–834.0)
0.6 (0.4–0.8)
59.0 (47.0–80.0)
26.5 (22.2–30.0)
23.37 (17.28–25.55)
48.70 (26.88–51.10)
DIH
Mean ± SD
680.6 ± 159.7
0.64 ± 0.09
59.8 ± 13.8
25.9 ± 2.3
23.87 ± 2.49
38.98 ± 12.90
Median (range)
699.0 (380.0–858.0)
0.6 (0.5–0.8)
63.5 (36.0–75.0)
26.2 (21.6–28.9)
23.95 (20.39–27.74)
37.07 (23.09–56.56)
ANOVA test
NS
NS
NS
NS
NS
NS
The results are presented as mean ± SD and median (range). Statistically significant differences between the groups have been shown, the levels of significance in the 95% confidence interval.