Synergy between HDAC and PARP Inhibitors on Proliferation of a Human Anaplastic Thyroid Cancer-Derived Cell Line

<div>Combination of SAHA and PJ34 induces apoptosis in SW1736 cell line. In (a) Annexin V (FITC) and propidium iodide (PI) staining of anaplastic thyroid cancer cell line after 72 h treatment with SAHA 1 <i>μ</i>M, PJ34 15 <i>μ</i>M alone or in combination. In (b) representation of Annexin V-positive/PI-negative cells.</div>

International Journal of Endocrinology

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Figure 3

Figure 3: Synergy between HDAC and PARP Inhibitors on Proliferation of a Human Anaplastic Thyroid Cancer-Derived Cell Line 