FGF21 Is Associated with Acanthosis Nigricans in Obese Patients
Table 1
Patients’ characteristics and blood test results ().
OB
AN
CON
M/F
19/21
18/22
13/27
Age (year)
35.65 ± 9.83
30.25 ± 9.28
24.4 ± 7.6
Height (cm)
164.5 ± 7.0
166.7 ± 8.8
162.1 ± 5.3
Neck circumference (cm)
38.3 ± 3.3
38.6 ± 6.2
31.1 ± 2.6
Waist circumference (cm)
101.2 ± 9.5
104.9 ± 17.8
71.2 ± 6.0
Hip circumference (cm)
105.0 ± 8.1
111.7 ± 13.5
92.1 ± 3.0
Waist/hip ratio
0.964 ± 0.062
0.937 ± 0.076
0.772 ± 0.048
Percentage of body fat (%)
37.3 ± 4.0
35.5 ± 4.4
25.1 ± 4.5
Visceral fat fraction
16.5 ± 5.8
15.5 ± 7.0
3.6 ± 3.6
Basal metabolic rate (kcal/d)
1741.4 ± 239.5
1764.6 ± 322.7
1249.0 ± 160.2
BMI
33.6 ± 4.2
33.8 ± 6.5
21.1 ± 2.0
FFA (mmol/L)
0.58 ± 0.17
0.73 ± 0.23
0.54 ± 0.21
CRP (mg/L)
4.95 ± 3.71
4.35 ± 2.94
0.39 ± 0.35
UA (mol/L)
405.61 ± 97.86
442.99 ± 118.99
268.85 ± 67.70
TC (mmol/L)
4.85 ± 1.25
5.46 ± 1.64
4.19 ± 0.80
TG (mmol/L)
1.94 ± 1.29
2.26 ± 1.70
0.90 ± 0.80
TSH (mU/L)
2.01 ± 1.10
2.68 ± 1.23
3.08 ± 1.62
HOMA-IR
5.82 ± 3.59
8.22 ± 4.11
2.03 ± 0.74
OB: simple obese group. AN: obese group with acanthosis nigricans. CON: control group. BMI: body mass index. M/F: male/female. FFA: free fatty acid. CRP: C reactive protein. UA: uric acid. TC: total cholesterol. TG: triglyceride. TSH: thyroid stimulating hormone. HOMA-IR: homeostasis model of assessment for insulin resistance. Versus CON: , ; versus OB: .
