Research Article

The Impacts of SLC22A1 rs594709 and SLC47A1 rs2289669 Polymorphisms on Metformin Therapeutic Efficacy in Chinese Type 2 Diabetes Patients

Table 2

Comparisons of allelic frequencies of SLC22A1 rs594709 and SLC47A1 rs2289669 polymorphisms in T2DM patients and healthy subjects.

GenotypeT2DM patients
()
Healthy controls
()
value

SLC22A1 rs594709
 AA146 (54.68%)95 (52.20%)0.927
 GA99 (37.08%)70 (38.46%)
 GG22 (8.24%)17 (9.34%)
Alleles
 A391 (73.22%)260 (71.43%)0.555
 G143 (26.78%)104 (28.57%)
SLC47A1 rs2289669
 AA77 (28.84%)49 (26.92%)0.669
 GA128 (47.94%)95 (52.20%)
 GG62 (23.22%)38 (20.88%)
Alleles
 A282 (52.81%)193 (53.02%)0.950
 G252 (47.19%)171 (46.97%)