Pharmacogenetics of Risperidone and Cardiovascular Risk in Children and Adolescents

Table 5

Average rank (Mann-Whitney test) of continuous variables evaluated in relation to the SNP alleles ().

SNP	Parameter		Average Rank
	Leptin
HTR2C rs3813929 (both genders)	Hemi/homozygous	115	59.17	0.044
	Heterozygotes	5	91.20
HTR2C rs3813929 (females)	Heterozygotes	5	9.10	0.704
	Homozygous	17	12.21
HTR2C rs3813929 (males)	Hemizygous C	85	48.16	0.232
	Hemizygous T	13	58.27
LEPR	Presence of allele A	93	57.04	0.043
	Absence of allele A	27	72.41
	ALT
LEP	Absence of allele G	16	44.84	0.053
	Presence of allele G	104	62.91
CYP2D6	Absence of allele C	113	58.60	0.016
	Presence of allele C	7	91.14
	HOMA-IR
MC4R	Absence of allele T	7	35.14	0.047
	Presence of allele T	113	62.07
CYP2D6	Heterozygotes	36	56.38	0.032
	Homozygous	84	62.27