Clinical Study

Rationale and Design of RNAFH Study: Effect of Rosuvastatin (10 mg/d) on Nonalcoholic Fatty Liver in Metabolic Syndrome Patients without Overt Diabetes Evaluated by 1H-Magnetic Resonance Spectroscopy

Figure 1

Flowchart showing the timetable of the RNAFH study. The total follow-up duration is 52 weeks. 1H-MRS will be performed at baseline and 52th week. Physical examination, lipid parameters, HOMA-IR, and safety indices including liver function, CK, renal function, and HbA1c will be measured at baseline, 4th, 16th, 28th, and 40th week, and 52nd week.