Association of Polymorphisms in Toll-Like Receptors 4 and 9 with Autoimmune Thyroid Disease in Korean Pediatric Patients

Table 1

Characteristics of 104 autoimmune thyroid disease patients.

Characteristics
Sex (F/M)	86/18
Age (years) at diagnosis	11.3 ± 3.2
Age (years) at enrollment	13.2 ± 3.5
HD/GD	44/60
HD condition at diagnosis
Euthyroid state	9 (20.5%)
Subclinical hypothyroid state	6 (13.6%)
Overt hypothyroid state	23 (52.3%)
Hyperthyroid state	6 (13.6%)
HD patients on T4 replacement	25 (56.8%)
Class of TAO
0 ~ 1 no sign ~ only sign	75
2 soft tissue involvement	7
3 proptosis	19
4 extraocular muscle involvement	3
5 corneal involvement	0
6 sight loss	0

AITD: autoimmune thyroid diseases; HD: Hashimoto’s disease; GD: Graves’ disease; TAO: thyroid-associated ophthalmopathy.