Thyroid-Related Protein Expression in the Human Thymus

Figure 2

Expression of thyroid-related proteins in the thymus. Expression of thyroid-related proteins evaluated by immunohistochemistry. Representative images of thymic tissues that stained positive (a) or negative (b) for thyroid-related protein expression. The positive stained cells in Hassall’s corpuscles (arrows) and in thymocytes (arrowheads) are indicated. The expression of thyroid-related protein was observed in normal thyroid tissue (c) and thyroid tissue obtained from a patient with Graves’ disease (d) as a positive controls. Representative images of isotype control are shown as a negative control. All images are magnified 400x, and the scale bars represent 50 μm (a, b, and d) and 20 μm (c). NIS, sodium iodide symporter; TSHR, thyroid-stimulating hormone receptor; TPO, thyroid peroxidase; Tg, thyroglobulin.

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