Intranasal Insulin Administration Does Not Affect LH Concentrations in Men with Diabetes

Table 1

LH concentrations before and after intranasal insulin or saline administration in men with diabetes.

Diabetes	Insulin			Saline			Mean difference (95% confidence interval)
	Baseline (0–120 minutes)	Posttreatment (135–300 minutes)		Mean baseline LH (0–120 minutes)	Mean LH after treatment (135–300 minutes)
Mean LH (IU/l)	7.7 ± 3.0	8.0 ± 3.4	0.17	7.8 ± 3.5	7.9 ± 4.3	0.86	0.3, [−1.2, 1.7]	0.70
Peak LH (IU/l)	9.2 ± 3.3	9.5 ± 3.7	0.33	9.2 ± 3.7	9.8 ± 5.0	0.50	−0.2, [−2.4, 2.0]	0.87
Number of LH pulses (per hour)	0.5 ± 0.3	0.5 ± 0.4	0.74	0.6 ± 0.3	0.3 ± 0.2	0.06	0.3, [−0.1, 0.6]	0.10
Glucose (mmol/l)	8.1 ± 1.6	7.6 ± 1.7	0.01	7.5 ± 1.2	6.7 ± 1.4	0.06	0.3, [−0.5, 1]	0.45

The penultimate column shows the mean difference between the two treatments.