Research Article

Intranasal Insulin Administration Does Not Affect LH Concentrations in Men with Diabetes

Table 2

LH concentrations before and after intranasal insulin or saline administration in healthy lean men.

LeanInsulinSalineMean difference (95% confidence interval)
Baseline (0–120 minutes)Posttreatment (135–300 minutes)Mean baseline LH (0–120 minutes)Mean LH after treatment (135–300 minutes)

Mean LH (IU/l)3.3 ± 1.43.4 ± 1.20.763.6 ± 0.93.8 ± 1.40.63−0.1, [−1.1, 0.9]0.83
Peak LH (IU/l)4.6 ± 2.05.0 ± 1.40.515.3 ± 1.85.4 ± 1.90.92−0.1, [−1.7, 1.5]0.89
Number of LH pulses (per hour)0.4 ± 0.20.4 ± 0.40.870.3 ± 0.30.3 ± 0.40.990.0, [−0.5, 0.5]0.90
Glucose (mmol/l)5.2 ± 0.74.9 ± 0.40.375.2 ± 0.55.1 ± 0.20.41−0.1, [−1, 0.8]0.74

The penultimate column shows the mean difference between the two treatments.