Research Article

C1q/TNF-Related Protein5 (CTRP5) as a Biomarker to Predict Metabolic Syndrome and Each of Its Components

Table 1

Anthropometric and biochemical parameters in MetS and healthy subjects.

VariablesControl ()MetS ()
Not adjustedAdjusted for age and sexAdjusted for age, sex, and BMI

Sex (male/female)37/5235/53NS
Age (year)54 ± 1256 ± 9<0.05
BMI (kg/m2)22.54 ± 2.2925.01 ± 2.68<0.01<0.01
FAT%28.1 (23.9–31.7)31.2 (25.8–35.9)<0.01<0.01NS
WHR0.87 ± 0.060.92 ± 0.05<0.01<0.01NS
SBP (mmHg)117.6 ± 13.3128.1 ± 11.5<0.01<0.01<0.01
DBP (mmHg)74.5 ± 9.577.7 ± 9.4<0.05NSNS
TG (mmol/L)1.10 (0.92–1.40)1.50 (1.04–2.64)<0.01<0.01<0.01
TC (mmol/L)4.81 ± 0.834.98 ± 0.94NSNSNS
HDL-C (mmol/L)1.40 ± 0.251.22 ± 0.28<0.01<0.01<0.01
LDL-C (mmol/L)2.82 ± 0.772.76 ± 0.82NSNSNS
FBG (mmol/L)5.34 (4.99–6.21)7.44 (5.90–9.53)<0.01<0.01<0.01
2-hOGTT (mmol/L)6.75 (5.64–11.05)11.67 (7.56–14.99)<0.01<0.01<0.05
FIns (mU/L)8.24 (6.03–12.04)12.13 (9.09–17.89)<0.01<0.01<0.01
HbA1c (%)5.55 (5.30–7.00)7.45 (6.07–8.50)<0.01<0.01<0.01
HOMA-IR2.05 (1.44–3.10)4.39 (3.05–6.84)<0.01<0.01<0.01
CTRP5 (μg/L)125.3 (105.3–154.8)109.1 (71.1–133.2)<0.01<0.01<0.05

Data are shown as means ± SD or median (interquartile range). MetS: metabolic syndrome; NS: not significant; BMI: body mass index; FAT%: the percentage of body fat; WHR: waist-to-hip ratio; SBP: systolic blood pressure; DBP: diastolic blood pressure; TG: triglyceride; TC: total cholesterol; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; FBG: fasting blood glucose; 2-hOGTT: 2-hour blood glucose after glucose overload; FIns: fasting insulin; HbA1c: glycated hemoglobin A1c; HOMA-IR: the homeostasis model assessment of insulin resistance.