C1q/TNF-Related Protein5 (CTRP5) as a Biomarker to Predict Metabolic Syndrome and Each of Its Components
Table 1
Anthropometric and biochemical parameters in MetS and healthy subjects.
Variables
Control ()
MetS ()
Not adjusted
Adjusted for age and sex
Adjusted for age, sex, and BMI
Sex (male/female)
37/52
35/53
NS
Age (year)
54 ± 12
56 ± 9
<0.05
BMI (kg/m2)
22.54 ± 2.29
25.01 ± 2.68
<0.01
<0.01
FAT%
28.1 (23.9–31.7)
31.2 (25.8–35.9)
<0.01
<0.01
NS
WHR
0.87 ± 0.06
0.92 ± 0.05
<0.01
<0.01
NS
SBP (mmHg)
117.6 ± 13.3
128.1 ± 11.5
<0.01
<0.01
<0.01
DBP (mmHg)
74.5 ± 9.5
77.7 ± 9.4
<0.05
NS
NS
TG (mmol/L)
1.10 (0.92–1.40)
1.50 (1.04–2.64)
<0.01
<0.01
<0.01
TC (mmol/L)
4.81 ± 0.83
4.98 ± 0.94
NS
NS
NS
HDL-C (mmol/L)
1.40 ± 0.25
1.22 ± 0.28
<0.01
<0.01
<0.01
LDL-C (mmol/L)
2.82 ± 0.77
2.76 ± 0.82
NS
NS
NS
FBG (mmol/L)
5.34 (4.99–6.21)
7.44 (5.90–9.53)
<0.01
<0.01
<0.01
2-hOGTT (mmol/L)
6.75 (5.64–11.05)
11.67 (7.56–14.99)
<0.01
<0.01
<0.05
FIns (mU/L)
8.24 (6.03–12.04)
12.13 (9.09–17.89)
<0.01
<0.01
<0.01
HbA1c (%)
5.55 (5.30–7.00)
7.45 (6.07–8.50)
<0.01
<0.01
<0.01
HOMA-IR
2.05 (1.44–3.10)
4.39 (3.05–6.84)
<0.01
<0.01
<0.01
CTRP5 (μg/L)
125.3 (105.3–154.8)
109.1 (71.1–133.2)
<0.01
<0.01
<0.05
Data are shown as means ± SD or median (interquartile range). MetS: metabolic syndrome; NS: not significant; BMI: body mass index; FAT%: the percentage of body fat; WHR: waist-to-hip ratio; SBP: systolic blood pressure; DBP: diastolic blood pressure; TG: triglyceride; TC: total cholesterol; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; FBG: fasting blood glucose; 2-hOGTT: 2-hour blood glucose after glucose overload; FIns: fasting insulin; HbA1c: glycated hemoglobin A1c; HOMA-IR: the homeostasis model assessment of insulin resistance.