Regulatory Effect of 1,25(OH)2D3 on TGF-β1 and miR-130b Expression in Streptozotocin-Induced Diabetic Nephropathy in Rats

Table 2

TGF-β1 mRNA and protein expression.

Groups	n	mRNA	Protein
		TGF-β1	TGF-β1
TGF-β1ov + control	6	2.24 ± 0.20	2.11 ± 0.31
DN + control	6	1.57 ± 0.17	1.58 ± 0.18
t		6.252	3.59
		<0.01	<0.01
TGF-β1si + control	6	0.93 ± 0.24	0.92 ± 0.41
DN + control	6	1.57 ± 0.17	1.58 ± 0.18
t		−5.33	−3.37
		<0.01	<0.01

Data are expressed as mean ± standard deviation. TGF-β1ov + control, TGF-β1 overexpression + oil; TGF-β1si + control, TGF-β1 siRNA + oil; DN + control, DN + oil.