Regulatory Effect of 1,25(OH)2D3 on TGF-β1 and miR-130b Expression in Streptozotocin-Induced Diabetic Nephropathy in Rats

Table 5

MiR-130b expression in DN rats.

Group	Number	MicroRNA-130b
TGF-β1ov + control	6	0.46 ± 0.09
TGF-β1ov + VD	6	0.70 ± 0.20
t		2.64
		<0.05
TGF-β1si + control	6	1.07 ± 0.32
TGF-β1si + VD	6	1.74 ± 0.39
t		3.19
		<0.05

Data are expressed as mean ± standard deviation. TGF-β1ov + control, TGF-β1 overexpression + oil; TGF-β1 ov + VD, TGF-β1 overexpression + 1,25(OH)2D3; TGF-β1si + control, TGF-β1 siRNA + oil; TGF-β1si + VD, TGF-β1siRNA + 1,25(OH)2D3.