Preoperative and Postoperative Bone Mineral Density Change and Risk Factor Analysis in Patients with a GH-Secreting Pituitary Adenoma
Table 3
Postoperative BMD Z score changes in patients with acromegaly.
Before surgery
After surgery
Control
P1
P2
L1-Z
0.600 ± 1.134
0.231 ± 1.176
−0.186 ± 1.116
0.037
0.292
L2-Z
0.546 ± 1.385
−0.046 ± 1.212
−0.190 ± 1.110
0.006
0.720
L3-Z
0.500 ± 1.466
0.115 ± 1.289
0.279 ± 1.234
0.029
0.703
L4-Z
0.477 ± 1.705
0.008 ± 1.552
0.231 ± 1.392
0.031
0.661
L1–L4-Z
0.539 ± 1.433
0.046 ± 1.279
0.059 ± 1.150
0.012
0.976
L2–L4-Z
0.508 ± 1.532
0.023 ± 1.357
0.128 ± 1.202
0.012
0.814
Femoral neck-Z
1.023 ± 1.073
1.269 ± 1.085
0.332 ± 0.796
0.019
0.012
Ward triangle-Z
0.231 ± 1.154
0.331 ± 1.261
−0.232 ± 0.830
0.240
0.160
Trochanter-Z
0.415 ± 1.049
0.477 ± 1.042
−0.082 ± 0.855
0.619
0.107
Total hip-Z
0.585 ± 1.130
0.777 ± 1.173
0.193 ± 0.787
0.040
0.121
The patients with nonfunctioning pituitary adenoma were regarded as the control. P1: value of the comparison between preoperative and postoperative BMD; P2: value of the comparison between the postoperative and control group.
