PDE5A Suppresses Proteasome Activity Leading to Insulin Resistance in C2C12 Myotubes

<div>Effects of PDE5A on the proteasome activity in C2C12 myotubes. (a) Effects of PDE5A overexpression (OE) on the GFPu protein levels; (b) effects of PDE5A knockdown (KD) on the GFPu protein levels; (c) effects of PDE5A overexpression on the chymotrypsin-like activity of proteasome; (d) effects of PDE5A knockdown on the chymotrypsin-like activity of proteasome. 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International Journal of Endocrinology

fig4

Figure 4

Figure 4: PDE5A Suppresses Proteasome Activity Leading to Insulin Resistance in C2C12 Myotubes 