Gonadal and Cortisol Hormone Profile among Male Chronic Khat, Marijuana, and Heroin Abuses

Table 2

Gonadal and cortisol hormone parameters between drug abuse and control groups at Zewditu Hospital, Ethiopia, in 2017.

Type of drug abuse	N (%)	Hormonal parameters	Median (control group)	Median (drug abuser)	value
Khat	21 (14.2)	Cortisol	15.02	16.23	0.934
		E2	22.59	39.42	0.003
		FSH	3.22	3.24	0.869
		LH	6.16	4.97	0.003
		Testosterone	7.95	6.07	0.03
Marijuana	61 (41.2)	Cortisol	15.02	14.01	0.120
		E2	22.59	43.93	<0.001
		FSH	3.22	3.01	0.055
		LH	6.16	5.01	0.021
		Testosterone	7.95	6.31	0.01
Heroin	66 (44.6)	Cortisol	15.02	17.2	0.120
		E2	22.59	40.15	<0.001
		FSH	3.22	2.37	0.055
		LH	6.16	5.65	0.021
		Testosterone	7.95	6.62	0.004

Cortisol (μg/dL), E2 (pg/mL), FSH (lu/L), LH (lu/L), and testosterone (ng/dl) Mann–Whitney test significant (value <0.05). Reference range (LH: 1.24–7.8 IU/L, FSH: 2–15 IU/L, testosterone: 2.7–10.7 ng/dL, estradiol: 10–40 pg/ml, and cortisol: 10–20 μg/dl).