MC4R Single Nucleotide Polymorphisms Were Associated with Metabolically Healthy and Unhealthy Obesity in Chinese Northern Han Populations
Table 6
Associations of SNPs in MC4R gene with DBP in all subjects.
SNP variables
Genotype
rs2331841
AA
AG
GG
DBP (mmHg)
82.06 (78.70, 85.42)
82.92 (81.42, 84.41)
80.44 (79.34, 81.54)
0.023
0.033
0.059
rs6567160
CC
CT
TT
DBP (mmHg)
81.40 (77.94, 84.86)
83.20 (81.70, 84.70)
80.36 (79.27, 81.45)
0.011
0.014
0.030
rs571312
AA
AC
CC
DBP (mmHg)
81.88 (78.22, 85.54)
83.24 (81.72, 84.76)
80.36 (79.27, 81.45)
0.012
0.013
0.033
rs17782313
CC
CT
TT
DBP (mmHg)
80.40 (79.32, 81.49)
83.15 (81.63, 84.68)
81.81 (78.34, 85.27)
0.020
0.021
0.047
rs12970134
AA
AG
GG
DBP (mmHg)
81.38 (76.48, 86.27)
82.86 (81.29, 84.42)
80.66 (79.60, 81.72)
0.033
0.034
0.151
rs11872992
AA
AG
GG
DBP (mmHg)
81.46 (78.36, 84.24)
82.23 (81.01, 83.45)
80.98 (79.21, 82.68)
0.164
0.270
0.830
ANOVA (one-way analysis of variance) analysis between three genotypes. Comparison of the genotypes under the dominant model. Logistic regression analysis between three genotypes and DBP after adjusting for sex, age, and BMI. DBP: diastolic blood pressure.
