Research Article

TG : HDL-C Ratio Is a Good Marker to Identify Children Affected by Obesity with Increased Cardiometabolic Risk and Insulin Resistance

Table 1

Clinical characteristics of 232 children by gender.

Boys (n = 114, 49.2%)Girls (n = 118, 50.8%)X2 valueAll

Age (mean ± SD)12.7 ± 2.013.3 ± 1.98NA0.02a12.6 ± 2.01
Pubertal status
 Prepubertal42 (37.2)29 (25.4)3.6320.0771 (31.3)
 Pubertal (Tanner stage ≥ 2)71 (62.8)85 (74.6)156 (68.7)
Abdominal obesity
 WC < 90th centile11 (9.6)15 (12.7)0.5470.4626 (11.2)
 WC ≥ 90th centile103 (90.4)103 (87.3)206 (88.8)
BMI z-score >1 or 2 SD
 Overweight17 (14.9)33 (28)5.8840.0250 (21.6)
 Obese97 (85.1)85 (72)182 (78.4)
Acanthosis nigricans
 Presence47 (42)74 (65.5)12.52<0.001121 (53.8)
 Absence65 (58)39 (34.5)104 (46.2)
Insulin resistance
 Prepubertal
  HOMA-IR < 2.615 (35.7)9 (31)0.1680.6824 (33.8)
  HOMA-IR ≥ 2.627 (64.3)20 (68.9)47 (66.2)
 Pubertal
  HOMA-IR < 435 (49.2)44 (54.3)0.0940.7679 (50.6)
  HOMA-IR ≥ 436 (50.8)41 (45.7)77 (49.4)
Liver enzyme test
 Low risk (ALT : AST >1)97 (85.1)104 (88.1)0.4650.495201 (86.6)
 High risk (ALT : AST≤1)17 (14.9)14 (11.9)31 (13.4)
Metabolic syndrome
 Nonmetabolic syndrome101 (88.6)108 (91.5)0.5570.455209 (90.1)
 With metabolic syndrome13 (11.4)10 (8.5)23 (9.9)

aIndependent-group t-test; NA: not available.