TG : HDL-C Ratio Is a Good Marker to Identify Children Affected by Obesity with Increased Cardiometabolic Risk and Insulin Resistance
Table 4
Comparison of metabolic syndrome-associated risk factors between children with metabolic syndrome (MetS) and elevated TG : HDL-C ratio (TG : HDL-C ≥ 1.11).
Biochemical/clinical parameters
Boys (n = 45)
Girls (n = 42)
Elevated TG : HDL-C ≥1.11 (n = 32, 71.1%)
MetS (n = 13, 28.9%)
value
TG : HDL-C ≥1.11 (n = 32, 75%)
MetS (n = 10, 25%)
value
Age
12.6 ± 1.97
13.1 ± 1.26
0.482
12.6 ± 1.9
13.2 ± 1.5
0.46
Cardiovascular risk factors
Obesity
Mean BMI z-score
2.9 ± 0.9
2.88 ± 0.6
0.95
2.6 ± 0.7
2.5 ± 0.5
0.78
Mean body fat (%)
38.5 ± 7.3
39.7 ± 4.9
0.623
42.6 ± 4.9
43.9 ± 3.7
0.337
Blood lipids
Mean total cholesterol (mmol/l)
4.68 ± 0.78
4.37 ± 0.9
0.253
4.5 ± 0.91
4.67 ± 0.9
0.623
Mean LDL-C (mmol/l)
3.33 ± 0.84
3.2 ± 1.14
0.636
3.2 ± 0.98
3.4 ± 0.74
0.439
Blood pressure
Mean systolic blood pressure (mmHg)
112 ± 9
116 ± 11
0.26
108 ± 12
111 ± 9
0.476
Mean diastolic blood pressure (mmHg)
73 ± 8
75 ± 8
0.468
69 ± 10
70 ± 7
0.885
Insulin resistance markers
Mean TG : HDL-C
1.44 ± 0.33
1.69 ± 0.83
0.17
1.34 ± 0.25
1.66 ± 0.77
0.045
Mean insulin
21.68 ± 13.44
22.54 ± 22.54
0.844
20.6 ± 11.9
26.7 ± 23.27
0.28
Liver enzymes/NAFLD blood markers
Mean ALT (U/l)
22.6 ± 17.3
19.23 ± 19.4
0.57
14.8 ± 10.9
22.2 ± 27.2
0.229
Mean AST (U/l)
32 ± 28.24
27.7 ± 24.76
0.634
23.3 ± 16.4
25.1 ± 21.6
0.80
Mean GGT (U/l)
34.0 ± 25.3
43.23 ± 64.9
0.507
21.2 ± 13.2
30.7 ± 19.9
0.09
Mean AST : ALT
1.64 ± 1.1
1.64 ± 0.62
0.98
2.36 ± 3.14
1.7 ± 1.1
0.64
value was obtained from comparison of means using the independent-group t-test; NA: not available.
