A Mechanism Exploration of Metabolic Syndrome Causing Nodular Thyroid Disease

Table 1

Anthropic and clinical characteristics of subjects with or without MS.

Variables	MS (n = 120)	Non-MS (n = 1948)		SMD
Age (years)	52.55 (13.65)	41.18 (13.39)	<0.001	0.841
Gender (female, n)	21 (17.5)	700 (35.9)	<0.001	0.426
Body mass index (kg/m^2)	27.32 (2.56)	23.55 (5.00)	<0.001	0.951
Systolic blood pressure (mmHg)	140.76 (16.84)	119.36 (11.85)	<0.001	1.470
Diastolic blood pressure (mmHg)	92.95 (9.78)	77.67 (9.09)	<0.001	1.618
Fasting blood sugar (mmol/L)	6.57 (1.79)	5.33 (0.95)	<0.001	0.859
Uric acid (mmol/L)	461.68 (112.29)	393.13 (95.72)	<0.001	0.657
Creatinine (mmol/L)	80.08 (17.99)	75.90 (20.15)	0.012	0.219
Triglyceride (mmol/L)	2.40 (1.34)	1.30 (0.89)	<0.001	0.970
Cholesterol (mmol/L)	5.43 (0.94)	4.87 (0.88)	<0.001	0.614
High-density lipoprotein (mmol/L)	1.17 (0.26)	1.42 (0.33)	<0.001	0.822
Low-density lipoprotein (mmol/L)	3.20 (0.82)	2.87 (0.75)	<0.001	0.419
Thyroid-stimulating hormone (mIU/L)	2.00 (1.01)	1.84 (0.93)	0.060	0.170
Free triiodothyronine (nmol/L)	5.20 (0.52)	5.18 (0.55)	0.686	0.039
Free thyroxine (nmol/L)	15.85 (2.09)	16.01 (2.21)	0.440	0.074
White blood cell (10^9 cells/L)	7.10 (2.11)	6.40 (1.60)	<0.001	0.376
Neutrophil (10^9 cells/L)	3.89 (1.52)	3.57 (1.20)	0.005	0.236
Lymphocyte (10^9 cells/L)	2.57 (0.79)	2.25 (0.61)	<0.001	0.452
Monocyte (10^9 cells/L)	0.43 (0.15)	0.39 (0.13)	0.001	0.273
Neutrophil/lymphocyte ratio	1.60 (0.63)	1.67 (0.69)	0.225	0.110
Lymphocyte/monocyte ratio	6.43 (2.27)	6.14 (2.08)	0.217	0.132
Monocyte/high-density lipoprotein ratio	0.39 (0.18)	0.30 (0.13)	<0.001	0.583
Thyroid nodules (n)	75 (62.5)	911 (46.8)	0.001	0.320

Data were presented as mean (S.D.) or number (%). MS: metabolic syndrome; SMD: standardized mean difference.