Research Article

A Mechanism Exploration of Metabolic Syndrome Causing Nodular Thyroid Disease

Table 2

Anthropic and clinical characteristics of subjects with or without MS based on propensity score matching.

VariablesMS (n = 118)Non-MS (n = 231)SMD

Age (years)51.96 (12.97)50.03 (14.10)0.2150.143
Gender (female, n)21 (17.8)37 (16.0)0.7870.047
Body mass index (kg/m2)27.36 (2.57)23.78 (2.99)<0.0011.282
Systolic blood pressure (mmHg)140.64 (16.95)122.05 (14.65)<0.0011.173
Diastolic blood pressure (mmHg)93.08 (9.81)79.47 (10.97)<0.0011.307
Fasting blood sugar (mmol/L)6.56 (1.80)5.50 (1.01)<0.0010.727
Uric acid (mmol/L)459.25 (111.30)454.59 (104.83)0.7000.043
Creatinine (mmol/L)79.87 (18.07)81.56 (17.28)0.3970.095
Triglyceride (mmol/L)2.41 (1.34)1.51 (1.03)<0.0010.752
Cholesterol (mmol/L)5.46 (0.91)5.06 (0.90)<0.0010.440
High-density lipoprotein (mmol/L)1.18 (0.26)1.33 (0.32)<0.0010.513
Low-density lipoprotein (mmol/L)3.22 (0.81)3.05 (0.77)0.0610.211
Thyroid-stimulating hormone (mIU/L)2.00 (1.02)1.76 (0.85)0.0200.258
Free triiodothyronine (nmol/L)5.21 (0.52)5.26 (0.54)0.3980.096
Free thyroxine (nmol/L)15.84 (2.10)15.88 (2.14)0.8830.017
White blood cell (109 cells/L)7.11 (2.12)6.63 (1.80)0.0260.246
Neutrophil (109 cells/L)3.91 (1.53)3.68 (1.32)0.1380.164
Lymphocyte (109 cells/L)2.57 (0.79)2.33 (0.65)0.0030.326
Monocyte (109 cells/L)0.43 (0.15)0.42 (0.14)0.5160.072
Neutrophil/lymphocyte ratio1.61 (0.63)1.65 (0.61)0.5290.071
Lymphocyte/monocyte ratio6.44 (2.29)6.08 (2.83)0.2300.141
Monocyte/high-density lipoprotein ratio0.38 (0.18)0.34 (0.15)0.0080.293
Thyroid nodules (n)73 (61.9)108 (46.8)0.0100.307

Matching variables included age, gender, uric acid, and creatinine. Data were presented as mean (S.D.) or number (%). MS: metabolic syndrome; SMD: standardized mean difference.