A Mechanism Exploration of Metabolic Syndrome Causing Nodular Thyroid Disease

Table 3

Association between MS and TNs based on propensity score matching.

Variables	MS (n = 114)	Non-MS (n = 219)		SMD
Age (years)	51.96 (12.97)	49.84 (14.20)	0.177	0.027
Gender (female, n)	21 (17.8)	41 (17.7)	1.000	0.016
Body mass index (kg/m^2)	27.36 (2.57)	23.51 (2.43)	<0.001	1.281
Systolic blood pressure (mmHg)	140.48 (16.82)	123.68 (12.06)	<0.001	1.148
Diastolic blood pressure (mmHg)	93.04 (9.73)	80.60 (8.55)	<0.001	1.359
Fasting blood sugar (mmol/L)	6.58 (1.83)	5.71 (1.80)	<0.001	0.478
Uric acid (mmol/L)	455.29 (109.43)	446.34 (104.02)	0.465	0.084
Creatinine (mmol/L)	80.11 (18.19)	77.88 (16.68)	0.263	0.128
Triglyceride (mmol/L)	2.39 (1.36)	1.69 (1.27)	<0.001	0.538
Cholesterol (mmol/L)	5.44 (0.91)	5.24 (0.95)	0.062	0.218
High-density lipoprotein (mmol/L)	1.18 (0.26)	1.27 (0.31)	0.010	0.309
Low-density lipoprotein (mmol/L)	3.21 (0.81)	3.20 (0.75)	0.910	0.013
Thyroid-stimulating hormone (mIU/L)	2.00 (1.03)	1.97 (0.98)	0.745	0.037
Free triiodothyronine (nmol/L)	5.21 (0.52)	5.22 (0.53)	0.783	0.032
Free thyroxine (nmol/L)	15.88 (2.09)	15.84 (1.99)	0.838	0.024
White blood cell (10^9 cells/L)	7.09 (2.14)	7.10 (2.01)	0.973	0.004
Neutrophil (10^9 cells/L)	3.92 (1.56)	3.92 (1.47)	1.000	0.000
Lymphocyte (10^9 cells/L)	2.53 (0.76)	2.53 (0.73)	0.959	0.006
Monocyte (10^9 cells/L)	0.43 (0.16)	0.43 (0.15)	0.816	0.027
Neutrophil/lymphocyte ratio	1.63 (0.63)	1.66 (0.92)	0.665	0.039
Lymphocyte/monocyte ratio	6.41 (2.31)	6.29 (1.96)	0.611	0.057
Monocyte/high-density lipoprotein ratio	0.38 (0.17)	0.37 (0.17)	0.558	0.067
Thyroid nodules (n)	71 (62.3)	127 (58.0)	0.523	0.088

Matching variables included age, gender, uric acid, creatinine, thyroid-stimulating hormone, free triiodothyronine, free thyroxine, white blood cell, neutrophil, lymphocyte, monocyte, neutrophil/lymphocyte ratio, lymphocyte/monocyte ratio, and monocyte/high-density lipoprotein ratio. MS: metabolic syndrome; TNs: thyroid nodules; SMD: standardized mean difference.