The Potential Link between Gut Microbiota and Serum TRAb in Chinese Patients with Severe and Active Graves’ Orbitopathy

Table 3

Associations between gut microbiota and GO-related traits.

Gut microbiota	TRAb		TGAb		CAS
	β		β		β
s_Prevotella_copri (OTU_2)	0.112	<0.001	−0.003	<0.001	0.060	0.946
s_Bacteroides_stercoris (OTU_5)	−0.066	0.006	−0.0003	<0.001	−0.215	0.619
g_Bacteroides (OTU_736)	−0.008	0.599	−0.0004	0.209	−1.225	0.002
f_Prevotellaceae (OTU_1068)	0.056	0.011	−0.0002	0.006	0.445	0.638
g_Bacteroides (OTU_1112)	−0.019	0.303	−0.0005	0.322	−1.286	<0.001

Negative binomial regressions were performed on gut microbiota after adjusting for age and sex. ; . CAS: clinical activity score; TGAb: antithyroglobulin antibody; TRAb: thyrotropin receptor antibody.