TET1 is a Tumor Suppressor That Inhibits Papillary Thyroid Carcinoma Cell Migration and Invasion

Figure 1

TET expression in PTC tissues and cell lines. (a) Relative expression level of TET1 was downregulated in PTC tissues compared with matched normal thyroid tissues (n = 49). (b) TET2 gene was significantly lowly expressed in PTC tissues compared with matched normal thyroid tissues (n = 49). (c) TET3 expression was not different in PTC and matched normal thyroid tissues (n = 49). (d) Relative expression levels of the TET family in PTC cell lines (BCPAP, K1, and TPC-1) compared with Nthy-ori 3-1 cells detected using qRT-PCR. (e) Expression levels of TET1 and TET3 proteins significantly decreased in PTC cells compared with Nthy-ori 3-1 cells as detected using Western blot assays. The data represented the mean ± SD from three independent experiments. , , and .

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