TET1 is a Tumor Suppressor That Inhibits Papillary Thyroid Carcinoma Cell Migration and Invasion

Figure 4

Results of miRNA chip and mRNA expression profiles after si-TET1 in BCPAP cells. (a) The expression of miRNAs and mRNAs was analyzed in NC and si-TET1 RNA groups in BCPAP cells. The fold change of miRNAs and mRNAs were set to be two times and 1.5 times, respectively, indicating obvious differences. The red ones are upregulated, and the green ones are downregulated. (b) Regulatory network map of classical oncogenes miR-7 and miR-15/16 and let-7. The statistically differentially expressed miRNAs are labeled in squares, and the statistically differentially expressed mRNAs are labeled in circles. The upregulated expression is shown in red, and the downregulated expression is shown in green.

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