Research Article

Pre- and Postoperative Health Status of Patients with Nonfunctioning and Secretory Pituitary Adenomas and an Analysis of Related Factors

Table 1

General data of the patients with pituitary adenomas.

Patients with pituitary adenomas

Male, n (%)118/41.4%
Age (years)43.7 ± 14.4
Body mass index (kg/m2)25.8 ± 4.3
Score of anxiety41.4 ± 8.4
Score of depression46.3 ± 10.5
Score of disease stigma35.6 ± 14.0
GH of patients with GH-secreting adenomas (ng/ml)10.2 (6.2, 31.6)
IGF-1 of patients with GH-secreting adenomas (ng/ml)827.0 (636.0, 1030.0)
Serum cortisol of patients with ACTH-secreting adenomas (μg/dl)30.8 (18.1, 37.4)
Serum ACTH of patients with ACTH-secreting adenomas (pg/ml)77.6 (45.6, 114.8)
24 h UFC of patients with ACTH-secreting adenomas (μg)519.2 (284.3, 743.9)
Recurrent tumor, n (%)62/21.8%
Macroadenomas, n (%)203/71.2%
Largest diameter of the tumor (cm)1.6 (0.6, 4.3)
Invasiveness tumor (Knosp >2), n (%)134/47.0%
Visual abnormalities, n (%)46/16.1%
Unmarried, n (%)45/15.8%
Unemployment, n (%)139/48.8%
Period of education (years)12.3 ± 4.1
Previous medical history, n (%)128/44.9%

GH = growth hormone; IGF-1 = insulin-like growth factor; ACTH = adrenocorticotropic hormone; UFC = urine free cortisol.