Pre- and Postoperative Health Status of Patients with Nonfunctioning and Secretory Pituitary Adenomas and an Analysis of Related Factors
Table 2
SF-36 scores of patients with pituitary adenomas in comparison with the reference values.
All patients with pituitary adenomas (n = 285)
Nonfunctioning adenomas (n = 147)
GH-secreting adenomas (n = 66)
ACTH-secreting adenomas (n = 35)
PRL-secreting adenomas (n = 24)
Reference range
Score
value
Score
value
Score
value
Score
value
Score
value
Physical component
PF
85.5 ± 19.2
0.271
87.3 ± 18.3
0.043
85.3 ± 15.8
0.572
71.9 ± 27.7
0.012
92.3 ± 11.8
0.003
84.2 ± 23.3
RP
63.8 ± 42.4
<0.001
71.3 ± 40.3
0.040
62.5 (0, 100)
<0.001
25 (0, 75)
<0.001
100 (75, 100)
0.960
80.9 ± 34.0
BP
78.6 ± 22.5
0.012
82.2 ± 21.9
<0.001
72.5 ± 23.2
0.353
74.6 ± 21.1
0.874
80.2 ± 22.5
0.286
75.2 ± 23.7
GHP
58.0 ± 21.2
<0.001
64.1 ± 20.9
<0.001
49.4 ± 19.4
<0.001
48.4 ± 19.7
<0.001
58.7 ± 18.4
0.002
71.9 ± 20.3
Mental component
SF
74.5 ± 22.3
<0.001
79.1 ± 21.9
0.021
72.0 ± 21.5
<0.001
61.4 ± 21.3
<0.001
75.5 ± 20.4
0.074
83.3 ± 22.7
MH
68.1 ± 18.8
<0.001
71.8 ± 19.0
0.043
64.7 ± 16.6
<0.001
60.6 ± 22.2
0.001
67.2 ± 13.9
0.014
74.7 ± 18.1
RE
62.1 ± 41.9
<0.001
71.9 ± 39.0
0.004
66.7 (0, 100)
<0.001
0 (0, 100)
<0.001
66.7 (66.7, 100)
0.151
81.3 ± 33.0
VT
67.5 ± 20.6
<0.001
73.2 ± 20.1
<0.001
61.2 ± 21.8
0.908
59.3 ± 17.8
0.594
63.8 ± 15.8
0.387
60.9 ± 20.9
PF = physical functioning; RP = role limitations due to physical health problems; BP = bodily pain; GHP = general health perceptions; SF = social functioning; MH = general mental health; RE = role limitations due to emotional problems; VT = vitality-energy or fatigue; GH = growth hormone; ACTH = adrenocorticotropic hormone; PRL = prolactin. values represent comparisons between patients with different types of pituitary adenomas and healthy population reference values. Patients with TSH-secreting adenomas (n = 8), FSH-secreting adenomas (n = 1), and GH/PRL-secreting adenomas (n = 4) were not included in this chart.
