International Journal of Endocrinology

Research Article

Pre- and Postoperative Health Status of Patients with Nonfunctioning and Secretory Pituitary Adenomas and an Analysis of Related Factors

Table 4

Relevance of clinical factors for health status in patients with pituitary adenomas.


		PF	RP	BP	GHP	VT	SF	RE	MH

Score of anxiety	r value	−0.39	−0.346	−0.482	−0.531	−0.612	−0.438	−0.419	−0.575
Score of anxiety	value	<0.001	<0.001	<0.001	<0.001	<0.001	<0.001	<0.001	<0.001

Score of depression	r value	−0.353	−0.384	−0.441	−0.507	−0.667	−0.488	−0.454	−0.641
Score of depression	value	<0.001	<0.001	<0.001	<0.001	<0.001	<0.001	<0.001	<0.001

Score of disease stigma	r value	−0.290	−0.375	−0.415	−0.498	−0.512	−0.528	−0.471	−0.519
Score of disease stigma	value	<0.001	<0.001	<0.001	<0.001	<0.001	<0.001	<0.001	<0.001

Age (years)	r value	−0.274	−0.043	−0.014	0.057	0.169	0.076	0.039	0.189
Age (years)	value	<0.001	0.473	0.812	0.335	0.004	0.198	0.516	0.001

Period of education (years)	r value	0.194	0.199	0.078	0.044	0.096	0.066	0.148	−0.641
Period of education (years)	value	0.001	0.001	0.187	0.457	0.105	0.265	0.012	0.813

Yearly income (dollars)	r value	0.167	0.194	0.051	0.118	0.102	0.096	0.187	0.112
Yearly income (dollars)	value	0.005	0.001	0.392	0.047	0.085	0.105	0.002	0.058

Body mass index (kg/m²)	r value	−0.200	−0.165	−0.088	−0.116	0.017	−0.053	−0.032	0.107
Body mass index (kg/m²)	value	0.001	0.005	0.140	0.051	0.779	0.370	0.593	0.071

Serum cortisol (μg/dl)	r value	−0.167	−0.146	−0.170	−0.060	−0.054	−0.142	−0.150	−0.059
Serum cortisol (μg/dl)	value	0.354	0.416	0.344	0.741	0.764	0.430	0.406	0.742

Serum ACTH (pg/ml)	r value	0.075	0.188	0.017	0.050	0.172	0.307	0.155	0.037
Serum ACTH (pg/ml)	value	0.670	0.280	0.924	0.777	0.324	0.073	0.374	0.834

24 h UFC (μg)	r value	0.083	0.156	0.071	0.032	−0.119	0.086	0.212	0.045
24 h UFC (μg)	value	0.659	0.395	0.699	0.862	0.517	0.639	0.244	0.806

GH (ng/ml)	r value	0.138	−0.084	−0.187	−0.100	−0.190	0.049	−0.195	−0.159
GH (ng/ml)	value	0.365	0.584	0.219	0.512	0.212	0.750	0.200	0.296

IGF-1 (ng/ml)	r value	0.066	−0.148	0.024	0.067	−0.081	−0.035	−0.133	−0.145
IGF-1 (ng/ml)	value	0.599	0.054	0.847	0.594	0.519	0.783	0.287	0.247

Sex	t/z value	1.607	‐0.733	0.361	1.542	0.408	0.172	‐0.583	0.641
Sex	value	0.109	0.464	0.718	0.124	0.683	0.863	0.560	0.522

Unmarried	t/z value	−1.648	−0.582	−0.559	−0.997	0.436	0.662	−0.683	1.771
Unmarried	value	0.100	0.560	0.576	0.320	0.663	0.509	0.494	0.078

Unemployment	t/z value	3.287	−1.638	0.929	−0.818	0.927	0.837	−0.593	0.136
Unemployment	value	0.001	0.101	0.354	0.414	0.355	0.403	0.553	0.892

Recurrent tumor	t/z value	−1.862	−0.827	−1.616	−2.245	0.019	−1.994	−1.331	−0.717
Recurrent tumor	value	0.064	0.408	0.107	0.026	0.985	0.047	0.183	0.474

Previous medical history	t/z value	−5.090	−2.629	−0.925	−3.308	−0.045	−1.319	−1.414	−0.426
Previous medical history	value	<0.001	0.009	0.355	0.001	0.964	0.187	0.157	0.670

PF = physical functioning; RP = role limitations due to physical health problems; BP = bodily pain; GHP = general health perceptions; SF = social functioning; MH = general mental health; RE = role limitations due to emotional problems; VT = vitality-energy or fatigue; GH = growth hormone; IGF-1 = insulin-like growth factor 1; ACTH = adrenocorticotropic hormone; UFC = urine free cortisol. .