Pre- and Postoperative Health Status of Patients with Nonfunctioning and Secretory Pituitary Adenomas and an Analysis of Related Factors
Table 6
Postoperative changes in health status in patients with pituitary adenomas.
All pituitary adenomas (n = 212)
Nonfunctioning adenomas (n = 125)
GH-secreting adenomas (n = 56)
ACTH-secreting adenomas (n = 31)
Preop. score
Postop. score
value
Preop. score
Postop. score
value
Preop. score
Postop. score
value
Preop. score
Postop. score
value
Physical component
PF
85.8 ± 19.2
80.2 ± 17.7
0.001
88.4 ± 16.8
82.5 ± 16.2
0.005
85.3 ± 16.1
78.2 ± 19.6
0.040
71.5 ± 28.7
71.5 ± 19.1
1.000
RP
62.6 ± 42.5
54.3 ± 42.4
0.036
69.0 ± 40.2
58.8 ± 41.7
0.049
62.5 (0, 100)
50 (0, 100)
0.698
25 (0, 75)
12.5 (0, 75)
0.770
BP
76.5 ± 24.1
77.0 ± 22.0
0.826
79.4 ± 24.5
79.9 ± 18.9
0.873
70.7 ± 23.9
76.4 ± 23.5
0.204
73.3 ± 23.2
64.0 ± 27.2
0.153
GHP
57.4 ± 21.1
62.9 ± 22.2
0.007
62.8 ± 21.2
66.7 ± 21.7
0.153
49.0 ± 19.5
57.8 ± 20.5
0.020
50.3 ± 19.7
58.0 ± 23.7
0.169
Mental component
SF
66.4 ± 21.2
67.5 ± 21.7
0.174
77.9 ± 21.7
78.8 ± 23.5
0.753
69.9 ± 22.2
76.3 ± 19.9
0.107
62.5 ± 21.9
66.9 ± 25.1
0.461
MH
67.6 ± 19.3
67.7 ± 20.0
0.955
71.6 ± 19.1
71.6 ± 18.9
1.000
63.8 ± 16.8
67.7 ± 17.2
0.224
58.6 ± 22.7
57.2 ± 24.4
0.814
RE
61.2 ± 41.8
61.9 ± 41.0
0.852
70.7 ± 38.5
67.5 ± 38.9
0.514
66.7 (0, 100)
67 (0, 100)
0.159
0 (0, 100)
33 (0, 91.75)
0.776
VT
66.4 ± 21.2
67.5 ± 21.7
0.559
72.0 ± 20.3
72.6 ± 20.0
0.790
59.6 ± 22.0
63.5 ± 19.2
0.327
58.4 ± 19.8
58.4 ± 26.2
1.000
PF = physical functioning; RP = role limitations due to physical health problems; BP = bodily pain; GHP = general health perceptions; SF = social functioning; MH = general mental health; RE = role limitations due to emotional problems; VT = vitality-energy or fatigue; GH = growth hormone; ACTH = adrenocorticotropic hormone; Preop. = preoperative; Postop. = postoperative. values represent comparisons between postoperative and preoperative scores on the SF-36 questionnaire. .
