Association of Genetic Variants of KCNJ11 and KCNQ1 Genes with Risk of Type 2 Diabetes Mellitus (T2DM) in the Indian Population: A Case-Control Study

Table 2

Genotypic and allelic distribution and association analysis of KCNJ11 rs5210 gene polymorphism and risk of T2DM under different genetic models.

Genotype/allele		Cases (n = 300)	Control (n = 100)	Odds ratio (95% CI)	value
AA		120 (40%)	58 (58%)	Ref	Ref
AG		136 (45.3%)	32 (32%)	2.05 (1.25–3.37)	0.004
GG		44 (14.6%)	10 (10%)	2.12 (0.99–4.5)	0.046
value −0.007
Recessive model	GG	44	10	1.54 (0.74–3.20)	0.239
	AG + AA	256	90
Dominant model	AG + GG	180	42	2.07 (1.30–3.27)	0.001
	AA	120	58
Codominant model	AG	136	32	1.76 (1.09–2.84)	0.020
	AA + GG	164	68
Allele
A		378 (63%)	148 (74%)	1.67(1.16–2.38)	0.004
G		222 (37%)	52 (26%)

OR: odds ratio, CI: confidence interval, n: number in sample.Significant at .